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Quinaldopeptin
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ADCs Toxins, Quinaldopeptin is a quinomycin antibiotic isolated from an Amycolatopsis sp. with strong antimicrobial and cytotoxic activity. The symmetric cyclic peptide structure of Quinaldopeptin contains two intercalating naphtyl moieties which produce a bis-intercalation of DNA base pairs, creating DNA crosslinks and disturbing natural DNA processes. Quinaldopeptin is demonstrated to have high efficacy against gram-positive bacteria and cultured B16 melanoma cells. Quinaldopeptin is related to sandramycin and luzopeptins. https://www.creative-biolabs.com/adc/classify-adc-toxins-6.htm
