Taxoids

Taxoids, also known as paclitaxel, are derivatives from taxol, an early potent anticancer compound extracted from Pacific yew (Taxus brevifolia Nutt). Taxiods was first discovered and named by Wall et al. in 1966 and their cytotoxcicity was later demonstrated in 9 KB cancer cell and tissue culture. Since then, taxiods have been documented to show anti-cancer activity against leukemia and murine melanoma cell cultures, as well as various xenograft mouse models bearing MX1 (breast), CX1 (colon) and LX1 (lung) carcinomas.To expand the application of taxoids in the form of innovated ADCs, Creative Biolabs offers comprehensive services to help design and create ADCs with tailored taxoids payloads, optimized linkers, and suitable conjugation strategies to meet clients’ unique requirements using our well-established “DrugLnk” synthesis platform. Creative Biolabs provides customized antibody-drug conjugates (ADCs) development services using various taxoids as payloads for targeted caner therapy. https://www.creative-biolabs.com/adc/taxoids.htm