Sam-E 400mg 60 Tabs by Now Foods DescriptionNervous System SupportSupports Emotional Well-BeingSupports Joint HealthEnteric CoatedGMP Quality AssuredA Dietary SupplementVegetarian/VeganSAMe (S-adenosylmethionine),a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to temporarily alleviate minor joint discomfort resulting from overexertion or stress. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.Suggested UseAs a dietary supplement, take 1 tablet 2 to 4 times daily, preferably on an empty stomach.Supplement FactsServing Size 1 Tablet Amount Per Serving%Daily ValueSAMe (S-Adenosyl-L-Methionine)(from 800 mg of S-Adenosyl-L-Methionine Disulfate Tosylate)400 mg** Daily Value not established. Other IngredientsCellulose, croscarmellose sodium, magnesium stearate (vegetable source), silica, stearic acid (vegetable source), ascorbic acid, citric acid and enteric coating (cellulose, triethyl citrate, methacrylic acid).Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.WarningsDo not eat freshness packets. Keep in bottle.For adults only. Individuals with bipolar (manic) depression and those with anxiety disorders should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.