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Tubulysin M
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ADCs Toxins, Tubulysins show a very high cytotoxic activity against in vitro and in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotheraprutics. Based on the SAR of the tubulysins this class allows for many chemical conjugation and targeting strategies which offer several different development opportunities. https://www.creative-biolabs.com/adc/classify-adc-toxins-6.htm
