This plant has been mentioned in early literature as a hypoglycaemic and anti-inflammatory agent. Its effect as an oral hypoglycemic has been evaluated. In rats trigonelline counteracts the hyperglycemic effect of cortisone given 2 hours before or simultaneously. Antiulcer property has been studied in rats. Hypocholesterolemic effects, and anti-inflammatory effects have been observed.
The ether extract of the seeds had an effect on inflammation induced in rats by cotton - pellet insertion, or formalin or carrageenin exposure, comparable to that of salicylates.
The antiarthritic property of methi seed powder is widely known in many parts of India. It forms an important medicinal use of the plant in rheumatic disorders and spondylosis. The drug is also used for chronic bronchitis and hepato and splenomegaly in the unani system of medicine. The seeds and leaves are also used in obesity.