For severe foot swelling and edema-Unisex. Very stretchy for the largest feet and ankle conditions. High bulk 100% cotton yarn is latex free. Over sized and preshrunk to maintain comfort in the worst conditions. Sized large enough to fit over most casts. Flat toe seam will never rub or irritate. Heel pocket allows more space in instep. Small(6-8 1/2) medium/large (9-11) Extra large (10-14). You will receive 6 pair each size. Machine washable Made in USA.